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Overview Differentiating upper motor neuron (UMN) from lower motor neuron (LMN) lesions is essential for neuro assessment and viva. Comparison Table Tone: UMN ↑ spasticity; LMN ↓ flaccidityReflexes: UMN hyperreflexia, Babinski +; LMN hyporeflexia/areflexiaPower: UMN weakness in pattern; LMN weakness in myotomeFasciculations: LMN present; UMN absentAtrophy: LMN marked; UMN mild/disuse Clinical Application Combine history, inspection, tone, reflexes, power grading, and functional tests (gait, hand function) before localizing the lesion.